Recombinant CEACAM5 (Tusamitamab Biosimilar) 抗体
This anti-CEACAM5 (Tusamitamab Biosimilar) antibody is a Humanized 单克隆 antibody detecting CEACAM5 (Tusamitamab Biosimilar) in FACS 和 in vivo. Suitable for 人.
Quick Overview for Recombinant CEACAM5 (Tusamitamab Biosimilar) 抗体 (ABIN7795147)
抗原
CEACAM5 (Tusamitamab Biosimilar)
抗体类型
Recombinant Antibody
适用
人
宿主
Humanized
克隆类型
单克隆
标记
This CEACAM5 (Tusamitamab Biosimilar) antibody is un-conjugated
应用范围
Flow Cytometry (FACS), In vivo Studies (in vivo)
质量等级
Research Grade
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Expression System
- Mammalian cells
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原理
- Tusamitamab Biosimilar, Human CEACAM5 Monoclonal Antibody
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产品特性
- What is tusamitamab biosimilar research grade? Tusamitamab is a humanized IgG1-kappa monoclonal antibody targeting carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) which is overexpressed in tumors including non-small cell lung cancer (NSCLC) and pancreatic ductal adenocarcinoma (PDAC), and is an attractive target for therapies based on CAR-T cell or/and ADCs. Tusamitamab ravtansine (SAR408701) is an antibody-drug conjugate (ADC) combining a humanized monoclonal antibody and a potent cytotoxic maytansinoid derivative (DM4) inhibiting microtubule assembly. Tusamitamab biosimilar uses the same protein sequences as the therapeutic antibody tusamitamab.
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纯化方法
- Protein A or G affinity column
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纯度
- >95 % by reducing SDS-PAGE
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内毒素水平
- < 1 EU per 1 mg of the protein by the LAL method
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免疫原
- Human CEACAM5
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anti-CEACAM5 (Tusamitamab Biosimilar) (E239D), (M241L) antibody
Research Grade 适用: 人 ELISA, FACS 宿主: 小鼠 Chimeric unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- > 3 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- CEACAM5 (Tusamitamab Biosimilar)
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别名
- Tusamitamab Biosimilar
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物质类
- Biosimilar
抗原
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